YWCA South Sudan was as established in 1997 as a women’s group in the local Anglican Church of Yambio, a town in Western Equatoria region of South Sudan. In 2001, the organization partnered with the other YWCA’s both within and outside East Africa. Partnership with other YWCAs enabled the founders of YWCA South Sudan to be trained and restructure the organization. By 2011, the organization was affiliated to the World YWCA and was later registered as National Non-governmental Organization in South Sudan.
Currently, YWCA South Sudan has seven branches located in the former South Sudan States of Western Equatoria, Central Equatoria and Western Bar el Ghazal. The organization’s head office is located in Yambio and a national coordination office in Juba. YWCA South Sudan’s work currently focuses on five thematic programs areas namely, improving protection and security for girls and women, Enhanced women’s and girls’ economic empowerment, Leadership capacity of young women and strengthening institutional governance.